Circadian Rhythm & Chronobiology
Research, products, and tools referenced in this module.12 resources available.
American Academy of Pediatrics policy statement calling for middle and high schools to start no earlier than 8:30 AM based on adolescent circadian biology.
Landmark Salk Institute study showing time-restricted feeding prevents metabolic disease independent of caloric intake.
The 2002 Science paper that discovered melanopsin in retinal ganglion cells, revolutionizing our understanding of how light affects circadian rhythms.
PNAS study demonstrating that evening light-emitting device use suppresses melatonin, delays circadian phase, and impairs next-morning alertness.
Journal of Applied Physiology study showing dose-dependent melatonin suppression from LED blue light exposure.
Comprehensive review of vitamin D's role in developing brain, including effects on cell differentiation, neurotrophic factors, and neurotransmitter synthesis.
Janbek et al. systematic review of associations between maternal vitamin D status and child neurodevelopmental outcomes.
Review of melatonin's role in protecting mitochondria from oxidative damage, explaining the cellular-level effects of circadian disruption.
International Journal of Molecular Sciences paper on melatonin's role in mitochondrial protection and fission/fusion dynamics.
Comprehensive review of associations between artificial light at night, melatonin suppression, sleep deprivation, and circadian disruption.
Therapeutic light box for morning use to advance circadian phase, treat SAD, and support natural wake. Look for 10,000 lux output at manufacturer-specified distance.
Amber or red-lens glasses that filter blue light for evening screen use. Look for glasses that block wavelengths below 500nm.
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