Module Resources

Dominguez-Bello et al. (2010) - Landmark study showing how vaginal vs C-section birth shapes initial bacterial colonization across body sites

Shao et al. (2019) - Nature study showing C-section babies have disrupted Bacteroides transmission and increased opportunistic pathogens

Yano et al. (2015) - Cell study demonstrating that spore-forming gut bacteria directly regulate serotonin production

Bravo et al. (2011) - PNAS study showing L. rhamnosus affects brain GABA receptor expression and anxiety behavior through the vagus nerve

Kang et al. (2017) - Open-label study showing microbiota transfer improved GI and behavioral symptoms in children with autism

Tan et al. (2014) - Comprehensive review of how dietary fiber and SCFAs affect gut and immune health

Shen et al. (2017) - Meta-analysis showing probiotics given near first antibiotic dose reduce CDI risk by 50%+

Chassaing et al. (2015) - Nature study showing common food additives disrupt gut bacteria and promote inflammation

Rooks & Garrett (2016) - Comprehensive review of microbiome-immune interactions in Nature Reviews Immunology

Ferretti et al. (2018) - Cell Host Microbe study on how maternal bacteria colonize infants from multiple body sites

O'Mahony et al. (2015) - Review of how gut bacteria influence tryptophan metabolism and brain function

Qin et al. (2010) - MetaHIT study establishing 3.3 million microbial genes in the gut, 150x more than the human genome

Vighi et al. (2008) - Review establishing that 70-80% of immune cells reside in gut-associated lymphoid tissue

Bonaz et al. (2018) - Review showing 80% of vagus nerve fibers are afferent (gut-to-brain), establishing the vagus as a key communication pathway

Sudo et al. (2004) - Landmark study showing germ-free mice have exaggerated stress responses reversible only by early microbial colonization

McDonald et al. (2018) - Citizen science study showing 30+ plant types per week associated with greater microbiome diversity

Wickens et al. (2018) - RCT showing L. rhamnosus HN001 reduces allergic disease prevalence through age 11 in high-risk infants

Gutiérrez-Castrellón et al. (2017) - Systematic review and network meta-analysis supporting L. reuteri for infantile colic treatment

Dethlefsen & Relman (2011) - PNAS study showing incomplete and individualized recovery of gut microbiota after repeated antibiotics

Baron et al. (2020) - Systematic review linking prenatal and infant antibiotic exposure with increased childhood asthma, eczema, and hay fever

Suez et al. (2014) - Nature study showing artificial sweeteners alter gut microbiome and induce glucose intolerance

Strachan (1989) - Original BMJ paper proposing the hygiene hypothesis based on hay fever and family size data

Rook et al. (2013) - Updated framework explaining how loss of ancestral microbial exposures leads to immune dysregulation

Ownby et al. (2002) - JAMA study showing early exposure to 2+ pets reduces allergic sensitization risk by age 6-7

Ege et al. (2011) - NEJM study showing farm children exposed to diverse microorganisms have lower asthma and atopy rates

Tun et al. (2017) - CHILD study showing household furry pets enrich beneficial gut bacteria in infants across birth scenarios

Rajindrajith et al. (2016) - Review establishing childhood constipation affects up to 30% of children worldwide

Lieberthal et al. (2013) - AAP clinical practice guideline on diagnosis and management of acute otitis media, supporting watchful waiting

L. rhamnosus GG probiotic packets for children - one of the most studied probiotic strains

Saccharomyces boulardii probiotic powder for antibiotic-associated diarrhea prevention